个人简介

吴正理，男，安徽宿松人，三级教授，博士研究生导师。现任水产学院副院长。

一、学习工作经历

2020.09-至今 西南大学水产学院 教授 博导，副院长

2014.02-2020.08西南大学动物科技学院水产系 教授 博导，系主任

2009.11-2014.02加拿大戴豪斯（Dalhousie）大学 微生物与免疫 博士后

2008.07-2009.11中南大学生命科学学院生物化学系 讲师

2002.09-2008.06西南大学特种经济动物饲养专业 农学博士（硕博连读）

1997.09-2001.06西南农业大学淡水渔业专业 农学学士

二、教学工作

主要讲授本科生《水产动物疾病学》、《水产动物免疫学》，研究生《现代水产动物医学》等。主编西南大学规划教材《水产微生物学实验》、《水产动物疾病学实验与实训》。

1.指导本科生获得第六届（2019）全国大学生水族箱造景技能大赛一等奖

2.指导本科生获得第一届（2019）“全国大学生水产技能大赛——病鱼常规检查与鱼病识别”项目特等奖

3.获西南大学教学成果一等奖（2020）

4.获西南大学优秀班主任（2023）

5.获西南大学优秀研究生导师（2021）

6.指导研究生获第二届（2021）渔菁英挑战赛二等奖、第三届（2023）渔菁英挑战赛三等奖

7.获西南大学优秀研究生团队（2021-2022，2022-2023）

8.获西南大学优秀教师（2022-2024）

9.指导研究生获重庆市优秀硕士学位论文（2022）

10.指导研究获重庆市研究生创新项目资助7人次

11.指导研究生获国家奖学金5人次

三、科学研究

主要从事水产微生物与免疫方面的研究。主持科研项目30余项，发表科研论文70余篇。

科研获奖：

1.荣获西南大学“十三五”科研工作先进个人荣誉称号（2021）

2.获教育部自然科学奖二等奖（2018）

3.获重庆市科技进步二等奖（2018）

4.获全国百篇优秀博士学位论文(2010)

5.获重庆市优秀博士学位论文（2009）

主持科研项目：

1.重庆市科学技术局重庆市技术创新与应用发展专项重点项目：鱼菜共生智能工厂关键技术及装备研发（2022-2024）

2.中国工程科技发展战略重庆研究院咨询项目：三峡库区渔业资源保护及可持续利用战略研究（2022-2023）

3.重庆市科学技术局自然科学基金面上项目：“PPAR-CPT1”信号通路调节三角帆蚌脂质代谢的分子机制研究（2022-2024）

4.国家自然科学基金面上项目：Calcineurin调节IgE介导肥大细胞脱颗粒的分子机制（2018-2021）

5.重庆市科委民生项目：鱼蚌综合养殖治理池塘水质技术研发与示范（2019-2020）

6.中央高校基本科研业务费创新团队项目：渔业资源环境与健康养殖（2015-2017）

7.教育部优秀博士学位论文专项：养殖水体底泥微生物与酶活性的研究（2014-2015）

近5年代表性论文（*为通讯作者）：

1. Xiaoqi Tang, Qinglin Yang, Zhouzhou Nan, Tao Wang, Yanhong Li,Zhengli Wu*. The potential compensatory mechanism between pmbA and tldD governing the virulence of Aeromonas veronii and its implications on the immune response in freshwater bivalve (Hyriopsis cumingii). Aquaculture, 595 (2025) 741524. (中科院一区).

2. Xiaoqi Tang, Qinglin Yang, Shaoyu Hu, Kefan Guo, Yanhong Li,Zhengli Wu*. Comparative transcriptome reveals importance of export apparatus subunit (ascR) in type III secretion system and its roles on biological properties, gene expression profiles, virulence and colonization of Aeromonas veronii.International Journal of Biological Macromolecules, 2024, 274:133270.(中科院一区)

3.龙凯,孙 瑜,李艳红,腾树君,吴正理*.三角帆蚌HcCnAα基因克隆及维氏气单胞菌感染后的表达.水产学报, 2024, 48(5):059404.

4. Jing Mei, Qinglin Yang, Liyan Jiang, Tao Wang, Yanhong Li, Xiaobo Yu,Zhengli Wu*.Immune protection of grass carp by oral vaccination with recombinant Bacillus methylotrophicus expressing the heterologous tolC gene. Fish and Shellfish Immunology, 2024, 151: 109701.（中科院一区)

5. Xiaoqi Tang, Tao Wang, Qinglin Yang, Sichun Zheng, Shuang Ma, Weizhi Yao, Yanhong Li,Zhengli Wu*.Potential benefits of Bacillus subtilis-mediated bioflocs in supplementary feeding on triangle sail mussels Hyriopsis cumingii: a pilot study of fluorescence-labeled floc-forming bacteria.Aquaculture Reports, 2024, 34: 101904.（中科院一区)

6. Sichun Zheng, Xiaoqi Tang, Qinglin Yang, Xicheng Zhou, Yanhong Li,Zhengli Wu*.Aeromonas veronii tolC modulates its virulence and the immune response of freshwater pearl mussels, Hyriopsis cumingii. Developmental and Comparative Immunology. 2024, 153:105137.（中科院三区)

7. Yue Li, Wentong Li, Lin Luo, Yuanyuan Ren, Wei Xing, Guanling Xu, Tieliang Li, Min Xue, Huanhuan Yu,Zhengli Wu*.Dietary lipid levels affect growth performance, lipid metabolism, antioxidant and immune status of Amur sturgeon,Acipenser schrenckii.Aquaculture Reports, 2023, 33: 101796.（中科院一区)

8. Kefan Guo, Yu Sun, Xiaoqi Tang, Xicheng Zhou, Mi Jiang, Qinglin Yang, Yanhong Li,Zhengli Wu*. Pathogenicity and inactivated vaccine treatment of Aeromonas veronii JW-4 on crucian carp. Microbial Pathogenesis, 2023, (183) 106315中科院三区)

9. Qinglin Yang, Jing Mei, Xiaoqi Tang, Tao Wang, Kai Long, Yang Liu, Yanhong Li, Xiaobo Yu, Weizhi Yao,Zhengli Wu*. Assessing the suitability of three purple soils for aquaculture by physiological responses in freshwater bivalves (Hyriopsis cumingii).Aquaculture, 2023, (575) 739765. (中科院一区)

10. Qinglin Yang, Xiaoqi Tang, Qingqing Zhou , Xicheng Zhou , Jing Mei , Xiaobo Yu ,Yanhong Li , Weizhi Yao ,Zhengli Wu*. Elucidation on potential utilization of Forsythia suspensa fruits in freshwater bivalve (Hyriopsis cumingii) culture against Aeromonas veronii infection.Industrial Crops & Products,2023, (201) 116963 (中科院一区)

11. Xicheng Zhou, Qinglin Yang, Kai Long, Xiaoqi Tang, Lijun Luo,Zhengli Wu *, Yanhong Li*.Effect of Bacillus cereus mutant strain S458-M on active phosphorus and crucian carp in culture systems.Aquaculture, 2023, (573) 739627 (中科院一区)

12.周青青，杨清麟，李月，李艳红，杨大成，吴正理*.新型氟喹诺酮衍生物对水产致病菌及其生物被膜的抑制作用研究.微生物学报，2023, 63(8): 3041-3053

13. Han Hu, Yong Long, Guili Song, Shaoxiong Chen, Zhicheng Xu, Qing Li, andZhengli Wu*. Dysfunction of Prkcaa Links Social Behavior Defects with Disturbed Circadian Rhythm in Zebrafish. Int. J. Mol. Sci. 2023, 24, 3849 (中科院二区)

14. Yu Sun, Kefan Guo, Xiaobo Yu, Yanhong Li, Weizhi Yao,Zhengli Wu*. Molecular and biochemical effects on metabolism and immunity of Hyriopsis cumingii fed with four different microalgae. Frontiers in Marine Science. 2022, 970781 (中科院一区)

15. Yu Sun, Xiaobo Yu, Weizhi Yao,Zhengli Wu*.Research progress in relationships between freshwater bivalves and algae. Ecotoxicology and Environmental Safety. 2022 (239): 113665 (中科院一区)

16.马爽，蒋弥，李艳红，刘炀，孙瑜，唐晓琪，吴正理*.一株松鼠葡萄球菌JS-1对鲫的致病性及其灭活疫苗保护作用研究.水产学报，2022, 46(9): 1669-1679

17. Yanhong Li, Lijun Luo, Qinglin Yang, Wenjin Zhang, Xiaoqi Tang, Xiaobo Yu,Zhengli Wu*.Bacillus methylotrophicusWM-1 enhances the immunity of grass carp againstAeromonas hydrophila. Aquaculture Research.2022;53:2464–2471(中科院三区)

18. Yu Sun, Yang Liu, Xiaobo Yu, Tao Wang, Qin Wang, Weizhi Yao,Zhengli Wu*. Combined effects of ration levels and temperature on immune responses of the triangle sail mussel Hyriopsis cumingii. Aquaculture Research. 2022, 53: 440-452 (中科院三区)

19. Xiaoqi Tang, Shuang Ma, Longlong Sun, Yanhong Li, Qinglin Yang, Xiaobo Yu *,Zhengli Wu *. Isolation, identification, and positive effects of potential probiotics onCarassius auratus. Aquaculture. 2022, 548: 737668. (中科院一区)

20. Qinglin Yang, Kefan Guo, Xicheng Zhou, Xiaoqi Tang, Xiaobo Yu, Weizhi Yao,Zhengli Wu*. Histopathology, antioxidant responses, transcriptome and gene expression analysis in triangle sail mussel Hyriopsis cumingii after bacterial infection. Developmental and Comparative Immunology. 2021, 124: 104175. (中科院一区)

21. Mi Jiang, Wenjin Zhang, Lijun Luo, Xiaoqi Tang, Yanhong Li, Xiaobo Yu,Zhengli Wu*. Effects of Bacillus methylotrophicus WM-1 on water quality dynamics and cultural fish in grass carp culture system. Aquaculture Research. 2021, 52: 3371-3380. (中科院三区)

22.李艳红，刘洁，吴正理*. CnAβ基因对大鼠RBL-2H3细胞脱颗粒的影响.畜牧兽医学报. 2021, 52(2):515-524

23. Qinglin Yang, Xiaobo Yu, Chunying Du, Xin Ni, Wenyu Li, Weizhi Yao,Zhengli Wu^⁎. Bacterial challenge undermines the innate immune response inHyriopsis cumingii. Aquaculture. 2021, 530: 735783. (中科院一区)

24. Qinglin Yang, Lijun Luo, Yanhong Jiang, Jiaojiao Zhang, Xiaoqi Tang, Mi Jiang,Zhengli Wu^⁎, Yanhong Li^⁎. A high amylase‐producing bacterial strain exhibiting the phosphorus‐dissolving ability, isolated from freshwater aquaculture pond. Aquaculture Research. 2020, 51：4315-4326. (中科院三区)

25. Qinglin Yang, Wenyu Li, Chunying Du, Yang Liu, Shang Ma, Xiaobo Yu, Weizhi Yao,Zhengli Wu^⁎. Emerging pathogens caused disease and mortality in freshwater mussels, Hyriopsis cumingii, in China. Aquaculture Research. 2020, 51: 5096-5105. (中科院三区)

26. Longlong Sun, Yu Sun, Mi Jiang, Lijun Luo, Xiaobo Yu, Weizhi Yao,Zhengli Wu^⁎. Isolation, identification and pathogenicity of Proteus vulgaris from moribund common carp (Cyprinus carpio) farmed in China. Aquaculture. 2020, 525:735294 (中科院一区)

27. Yanhong Jiang, Mi Jiang, Yu Sun, Bo Xiong, Hongfang Qi, Shengqi Su, Jianquan Shi, Weizhi Yao,Zhengli Wu*. Comparisons of fecundity and reproductive hormone levels in three populations ofGymnocypris przewalskii. Aquaculture. 2020, 514:734449. (中科院一区)

28. Yanhong Li, Jie Liu, Jiaojiao Zhang, Wenjing Zhang,Zhengli Wu*. Characterization of microRNA profile in IgE-mediated mouse BMMCs degranulation. Journal of Microbiology, Immunology and Infection. 2020, 53: 550-560. (中科院二区)

29. Jie Liu, Yanhong Li, Fuping Ma, Shengqi Su, Weizhi Yao,Zhengli Wu*. Spatiotemporal variation of microbial community structure and physicochemical parameters in grass carp culture ponds. Journal of Freshwater Ecology. 2019, 34(1): 123-133. (中科院二区)

30.章文锦,张皎皎,李艳红,蒋艳红,姚维志,吴正理*.蜡状芽孢杆菌S458-1对水产养殖系统中水质调节的作用.微生物学报. 2019，59(11): 2182-2193.

四、社会兼职

重庆市生态渔业产业技术体系副首席

重庆市三区科技特派员

重庆市水产学会理事

重庆微生物学会理事

五、联系方式

邮箱:zh20140202@swu.edu.cn; 29596039@qq.com。

通讯地址：重庆市北碚区天生路2号西南大学水产学院400715

欢迎对水产动物病害、水产微生物与免疫感兴趣的学生加入团队。