个人简介

徐红艳，女，湖北省石首市（县）人，教授，博导。

一、学习工作经历

2020.10至今西南大学水产学院 教授 硕导、博导

2014.01-2020.09中国水产科学研究院珠江所 副研究员、研究员

2007.08-2013.12新加坡国立大学理学院、医学院 博士后

2005.09-2007.07华东理工大学生物工程学院 博士后

2003.01-2004.04 新加坡国立大学理学院 研究助理

2001.09-2004.07 中国科学院水生生物研究所遗传学理学博士

1994.09-1998.07 华中农业大学水产学院水产养殖农学学士、硕士

二、教学工作

讲授课程：本科生水产动物遗传育种学、细胞生物学；

研究生分子生物学研究技术、学术规范与论文写作。

教书育人理念：以爱为舟，以教为帆，启迪心智，塑造灵魂，成就未来。

教学成果：荣获水产动物遗传育种学重庆市2022高校课程思政教学名师和团队；重庆市线下一流课程-水产动物遗传育种学；连续两年指导本科生论文分别获得重庆市优秀论文、校优秀论文。

三、科学研究

（一）主要研究方向

1.水生动物生殖干细胞发育分化机制、细胞培养及细胞工程育种技术研究；

2.水生动物细胞种质资源库的构建与利用技术研究；

3.鱼类转基因育种技术及应用研究。

（二）主持的代表性科研项目

1.科技部, 国家重点研发计划项目课题任务, 2022YFD24009021，2022.11至2026.1。

2.国家自然科学基金委员会, 面上项目, 31873035，2019-01-01 至 2022-12-31。

3.科技部, 国家重点研发计划“蓝色粮仓科技创新”重点专项, 2018YFD0900203，2019-01-01 至 2022-12-31。

4.广东省科技厅，广东省科技计划协同创新与平台建设国际合作项目，编号2016A050502029，2016.08至2018.07。

5.农业部，国家农业部948引进项目，编号2015Z019，2015.1-12。

6.科技部，国家高技术研究发展计划（海洋“863”计划）项目，编号2006AA09Z436，2006.11至2009.12。

7.中国博士后基金，国家博士后基金特别资助项目，2005.11至2008.09。

（三）代表性论文 （^*通讯作者论文）

相关研究成果在国内、外核心期刊发表论文数十篇，其中以通讯作者、第一作者发表论文50余篇。

Han Cui,Haoyu Zhu,Wenzhuo Ban,Yulin Li,Ruyi Chen,Lingli Li,Xiaoling Zhang,KailiChen,Hongyan Xu*.Characterization of Two Gonadal Genes, zar1 and wt1b, inHermaphroditic FishAsian Seabass (Lates calcarifer),(2024)Animals (Basel). Feb3;14(3):508.

Hongyan Xu*, Wenzhuo Ban, Jiaming Tian, Jianfei Xu, Zhimin Tan, Sendong Li, Kaili Chen, Mi Ou, Kaibin Li.The New Roles of traf6 Gene Involved in the Development of Zebrafish Liver and Gonads.(2024)Mar Biotechnol (NY).Oct;26(5):917-930.

Ruyi Chen† , Haoyu Zhu† , Xiaoling Zhang, Lingli Li, Jinglin Xu, Zhimin Tan, Jialin Su, Ke Feng, Kaili Chen* and Hongyan Xu*.Characterization and function analysis of 17-beta hydroxysteroid dehydrogenase 2 (hsd17b2) gene during sex-reversal in the ricefield eel (Monopterus albus).(2024)IntJ Mol Sci. Aug 21;25(16):9063.

Jianfei Xu, Yonglin Guo, Zhimin Tan, Wenzhuo Ban, Jiaming Tian, Kaili Chen,Hongyan Xu* . Molecular cloning and expression analysis ofrad51gene associated with gametogenesis in Chinese soft-shell turtle (Pelodiscus sinensis) . (2023)Gene 887 147729.

Kaili Chen ; Jianfei Xu; Wenzhuo Ban; Jiaming Tian; Zhiming Tan; Zhoukai Tang; Luo Lei; Wei Li; Xinping Zhu; Hongyan Xu*; The divergent and conserved expression profile of turtlenanoggene comparing with fish and mammals,(2022)Biology, 11(9): 1342-1342.

Xu, H.-Y*.; Hong, X.-Y.;Zhong, C.-Y.; Wu, X.-L.; Zhu, X.-P.Restoring Genetic Resource throughIn Vitro Culturing Testicular Cellsfrom the Cryo-Preserved Tissue ofthe American Shad (Alosa sapidissima).(2022)Biology , 11, 790.

Zhong, C.; Tao, Y.; Liu, M.;Wu, X.; Yang, Y.; Wang, T.; Meng, Z.;Xu, H*.;Liu, X*. Establishment of aSpermatogonial Stem Cell Line withPotential of Meiosis in aHermaphroditic Fish,Epinepheluscoioides.(2022)Cells , 11, 2868.

Liu, X.; Liu, F.; Xu, H.; Yang,Y.; Wang, Y.; Hong, X.; Li, W.; Yu, L.;Chen, C.; Xu, H*.; et al.Characterization of the In VitroCultured Ovarian Cells in the AsianYellow Pond Turtle (Mauremysmutica).（2022）Biology 11, 1404.

Chen, K.; Xu, J.; Ban, W.;Tian, J.; Tan, Z.; Tang, Z.; Lei, L.; Li,W.; Zhu, X.; Xu, H*. The Divergentand Conserved Expression Profile ofTurtle Nanog Gene Comparing withFish and Mammals.(2022)Biology , 11,1342.

Liu, X., Li,W., Yang, Y., Chen, K., Li, Y., Zhu, X., Ye, H., &Xu, H.*. Transcriptome profiling of the ovarian cells at the single-cell resolution in adult Asian seabass.(2021)Front Cell Dev Biol.

Ou, M., Mao, H., Luo, Q., Zhao, J., Liu, H., Zhu, X., Chen, K., &Xu, H.* . The DNA methylation level is associated with the superior growth of the hybrid fry in snakehead fish (Channa argusxChanna maculata). (2019)Gene, 703, 125-133.

Xu, H.*, Zhu, X.*, Li, W., Tang, Z., Zhao, Y., & Wu, X. . Isolation and in vitro culture of ovarian stem cells in Chinese soft-shell turtle (Pelodiscus sinensis). (2018)Journal of Cellular Biochemistry, 119(9), 7667-7677.

Xu, H.*,Li, C., Suklai, P., Zeng, Q., Chong, R., & Gong, Z*. . Differential sensitivities to dioxin-like compounds PCB 126 and PeCDF betweenTg (cyp1a:gfp)transgenic medaka and zebrafish larvae. (2018)Chemosphere, 192, 24-30.

Xu, H.*,Zhang, X., Li, H., Li, C., Huo, X., Hou, L., Gong, Z.*. Immune response induced by major environmental pollutants through altering neutrophils in zebrafish larvae.(2018)Aquatic Toxicology,201, 99-108.

Wong, Y. Q.^#,Xu, H.^#, Wu, Q., Liu, X., Lufei, C., Xu, X. Q., & Fu, X. Y. . STAT3-inducible mouse ESCs: a model to study the role of STAT3 in ESC maintenance and lineage differentiation. (2018)Stem Cells Int., 8632950

Xu, H.*,Li, C., Zeng, Q., Agrawal, I., Zhu, X., & Gong, Z.*. Genome-wide identification of suitable zebrafishDanio rerioreference genes for normalization of gene expression data by RT-qPCR. (2016)J Fish Biol, 88(6), 2095-2110.

Xu, H*., Li, C., Li, Y., Ng, G. H., Liu, C., Zhang, X., & Gong, Z.*. Generation ofTg(cyp1a:gfp)transgenic zebrafish for development of a convenient and sensitive in vivo assay for aryl hydrocarbon receptor activity. (2015)Mar Biotechnol (NY), 17(6), 831-840.

Xu, H., Lim, M., Dwarakanath, M., & Hong, Y*.. Vasa identifies germ cells and critical stages of oogenesis in the Asian seabass. (2014)Int J Biol Sci, 10(2), 225-235.

Li M, Shen Q, Wong FM, Xu Hongyan, Hong N, Zeng L, Liu L, Wei Q, Hong Y.Germ cell sex prior to meiosis in the rainbow trout.(2011)Protein Cell. Jan;2(1):48-54.

Xu, Hongyan., Li, Mingyou., Gui, Jianfang^*, & Hong, Yunhan^*. Fish germ cells. (2010)Sci China Life Sci, 53(4), 435-446.

Xu, H.,Li, Z., Li, M., Wang, L., & Hong, Y^*.Bouleis present in fish and bisexually expressed in adult and embryonic germ cells of medaka.(2009)PLoS One, 4(6), e6097.

Wei Wei,Hongyan Xu*,Qiyao Wang, Xiao Zhang, Kangmei Chang, Changwen Wu and Yuanxing Zhang*.Identification of differentially expressed genes inlarge yellow croaker(Pseudosciaena crocea) induced by attenuated liveVibrio anguillarum.(2009）Aquaculture.Volume 291(1-2):124-129.

Wei Wei,Haizhen Wu*,Hongyan Xu*,Tao Xu,Xiao Zhang,Kangmei Chang andYuanxing Zhang*.Cloning and molecular characterization of two complement Bf/C2 genes in large yellow croaker (Pseudosciaena crocea).(2009)Fish & Shellfish Immunology.; 27(2):285-95

Xu Hongyan, Li Mingyou, Gui Jianfang, Hong Yunhan.Cloning and expression of medaka dazl during embryogenesis and gametogenesis.(2007)Gene Expr Patterns. Jan;7(3):332-8.

Xu, H.,Gui, J., & Hong, Y.^*. Differential expression of vasa RNA and protein during spermatogenesis and oogenesis in the gibel carp (Carassius auratusgibelio), a bisexually and gynogenetically reproducing vertebrate.(2005)Dev Dyn, 233(3), 872-882.

Yunhan Hong^* , Tongming Liu , Haobin Zhao ,Hongyan Xu,Weijia Wang , Rong Liu , Tiansheng Chen, Jiaorong Deng , Jianfang Gui. Establishment of a normal medakafish spermatogonial cell line capable of sperm productionin vitro.(2004)Proc. Natl. Acad. Sci. U S A.101(21): 8011-6.

唐舟凯，张飘逸，储张杰^*，朱新平，李伟，吴栩灵，徐红艳^*。中华鳖dazl基因克隆及在生殖细胞中的表达分析。2019，水产学报,43(2):400-409。

朱彦雨，刘晓莉，王亚坤，李伟，洪孝友，朱新平^*，徐红艳^*。黄喉拟水龟性别调控相关lncRNA和mRNA的筛选及初步分析。2020, 水产学报, 44(12): 1961−1976。

四、研究生培养

在读研究生15名（博士3名、硕士12名）。

五、社会兼职

无

六、联系方式

Email:xhy20210104@swu.edu.cn。

通讯地址：重庆市荣昌区学院路160号西南大学水产学院 402460

或：重庆市北碚区天生路2号西南大学水产学院 400715